Accelerating vaccine innovation

A $50 million Project NextGen competition to advance microneedle patch-based RNA vaccines.

Learn about the prize

Accelerating the development of Lyme disease diagnostics

How five innovator teams are meeting an urgent need for better Lyme disease testing.

Meet the Phase 2 winners

Designing future-ready K-12 education environments

The Learning Landscapes Challenge is a $2.2 million competition to accelerate infrastructure solutions in education.

Learn about the challenge

Enhancing testing for lead in children

The $1 million Lead Detect Prize seeks advanced point-of-care blood lead tests.

Meet the Phase 1 winners

Advancing bioelectronic medicine

The Neuromod Prize is bridging the gap between early-stage research and clinical use, bringing innovative neuromodulation therapies to patients.

Meet the Phase 1 winners

Connecting students with space careers

U.S. Department of Education named eight winners of the Your Place in Space Challenge.

See the winning ideas

Building an ecosystem of support for innovation

An update on Mission Daybreak, VA’s multiyear initiative to support the development of promising suicide prevention innovations.

Read the update

Reimagining career navigation for adult learners

The U.S. Department of Education announced winners of the $1 million Future Finder Challenge.

Meet the winners

Delivering a solver support program

Luminary Labs will design and produce Phase 4bc of MagQuest on behalf of the National Geospatial-Intelligence Agency.

Read the announcement

Advancing technology education in rural high schools

The U.S. Department of Education announces grand-prize winner in the $600,000 Rural Tech Project.

Meet the Woodlake team

Thought Leadership

Lab Report

News, analysis, and timely truth-telling.

A $100 million initiative to protect our planet

The Bezos Earth Fund launches a Grand Challenge to multiply the impact of climate and nature efforts using modern AI.

Janna Gilbert named Partner at Luminary Labs

Luminary Labs establishes a partnership model to support continued growth and expansion.

Perspectives on pull mechanisms

What they are and why they matter: a pull mechanisms reading list.

Select Clients

We serve as thought partners to leaders tasked with going beyond business as usual. When it’s time to execute, we help make it real.


  • AstraZeneca
  • Celgene
  • Janssen
  • Merck & Co., Inc.
  • Pfizer
  • Sanofi


  • Gordon & Betty Moore Foundation
  • Grand Victoria Foundation
  • Heritage Provider Network
  • Humanity United
  • Joyce Foundation
  • Planned Parenthood
  • Robert Wood Johnson Foundation
  • Schmidt Futures
  • Siegel Family Endowment


  • NASA
  • National Geospatial-Intelligence Agency
  • National Institutes of Health
  • U.S. Coast Guard
  • U.S. Department of Education
  • U.S. Department of Health and Human Services
  • U.S. Department of Homeland Security
  • U.S. Department of Veterans Affairs
  • U.S. Food & Drug Administration