Improving math and science achievement

IES Learning Acceleration Challenges are identifying and testing interventions.

Learn more about the challenges

Designing technical assistance that supports innovation and innovators

How the Rural Tech Project has created time and space for convening, collaboration, and connection.

Read the case study

Advancing bioelectronic medicine

The Neuromod Prize is bridging the gap between early-stage research and clinical use, bringing innovative neuromodulation therapies to patients.

Meet the Phase 1 winners

Accelerating the development of Lyme disease diagnostics

The LymeX Diagnostics Prize aims to develop diagnostics that can accurately detect active Lyme disease infections in people.

Learn more about the competition

Reducing Veteran suicides

Mission Daybreak, a $20 million grand challenge from the U.S. Department of Veterans Affairs, is an opportunity to serve those who have served.

Learn more about the challenge

Designing a national challenge to inspire transformational STEM learning experiences

How CTE Mission: CubeSat brought space missions to high schools

Read the case study

Incubating a national cybersecurity teacher professional development initiative

How CTE CyberNet strengthened cybersecurity education in high schools

Read the case study

Exploring and developing innovative approaches to enhancing education

Luminary Labs awarded ED ARPA contract by the U.S. Department of Education.

Learn about the contract

Advancing artificial organs

KidneyX announced Phase 1 winners in the Artificial Kidney Prize.

Meet the winners

Redefining fast, accurate drug detection

How the Opioid Detection Challenge used open innovation to advance new hardware solutions.

Read the case study

Using open innovation to source unexpected solutions

How MagQuest embraced the benefits of prize competitions to meet a mission-critical challenge.

Read the case study

Thought Leadership

Lab Report

News, analysis, and timely truth-telling.

New roles filled by new Luminaries

Luminary Labs welcomes new Design Manager and launches work-based learning program.

What it’s like to work at Luminary Labs

A live “ask me anything” conversation with CEO Sara Holoubek.

Calibrating our shared compass

We had revisited our values before, but this time felt different.

Select Clients

We serve as thought partners to leaders tasked with going beyond business as usual. When it’s time to execute, we help make it real.


  • AstraZeneca
  • Celgene
  • Janssen
  • Merck & Co., Inc., Kenilworth
  • Pfizer
  • Sanofi


  • Gordon & Betty Moore Foundation
  • Grand Victoria Foundation
  • Heritage Provider Network
  • Humanity United
  • Joyce Foundation
  • Planned Parenthood
  • Robert Wood Johnson Foundation
  • Schmidt Futures
  • Siegel Family Endowment


  • NASA
  • National Geospatial-Intelligence Agency
  • National Institutes of Health
  • U.S. Coast Guard
  • U.S. Department of Education
  • U.S. Department of Health and Human Services
  • U.S. Department of Homeland Security
  • U.S. Department of Veterans Affairs
  • U.S. Food & Drug Administration